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SHP099 Size:5mg Sulforhodamine 101 is particularly well

SKU: 5504729754

4.3
USD90.00 USD128.00

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Description

Sulforhodamine 101 is particularly well suited for excitation by the 568 nm spectral line of the Ar – Kr mixed gas laser commonly used in many confocal laser-scanning microscopes or the 594 nm spectral line of the orange He-Ne laser

It is converted from 6-carboxytetramethylrhodamine (6-TAMRA) and has similar spectroscopic properties of 6-TAMRA

Product Name Pomalidomide-CO-C5-Br Synonyms Pomalidomide-4'-CO-C5-Br CAS Number 2227423-38-1 Related CAS Molecular Formula C19H20BrN3O5 Molecular Weight 450

722 SMILES: [O-]C(=O)C1=CC(=CC=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)C(=O)NCCCN=[N]#N Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

Product Name Thalidomide-O-acetamido-C3-OH Synonyms Thalidomide-4'-O-acetamido-C3-OH CAS Number n/a Related CAS Molecular Formula C18H19N3O7 Molecular Weight 389

SHP099 Size:5mg Sulforhodamine 101 is particularly wellSHP099 is a highly potent (IC50 = 0. 071uM),selective and orally bioavailable small molecule SHP2 inhibitor. The inhibiting SHP2 activity of SHP099 is through an allosteric mechanism. SHP099 suppresses RASERK signalling to inhibit the proliferation of receptor tyrosine kinase driven human cancer cells in vitro and is efficacious in mouse tumour xenograft models. Product Name SHP099 Synonyms CAS Number 1801747 42 1 Related CAS Molecular Formula

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